A set of four toiletry bottles sitting on a splash of blue water.

Fact Sheet: Potentially Toxic Chemicals in Personal Care Products



Funding Area

Special Projects Fund


June 4, 2018

Special Projects Fund

On a daily basis, Americans are exposed to many of the 80,000 chemicals currently used in the United States—few of which are adequately tested for their effects on health.

A growing body of scientific evidence shows that even the smallest dose of some chemicals can be harmful, including those found in commercial products such as cosmetics, personal care products, cleaning products, and children’s products.

Get a printable fact sheet on potentially toxic chemicals that are commonly found in everyday products.

Full List of References
  1. Environmental Working Group, “Why this matters – Cosmetics and your health,” https://www.ewg.org/skindeep/why-this-matters-cosmetics-and-your-health/#.WvcK2dMvzBI accessed May 2018.
  2. Ibid.
  3. Ibid.
  4. Campaign for Safe Cosmetics, “The Big Multinational’s Policies on the Use of Chemicals of Concern in Cosmetics,” http://www.safecosmetics.org/get-the-facts/big-7/, accessed May 2018.
  5. European Commission, “CMR Substances,” https://ec.europa.eu/growth/sectors/cosmetics/products/cmr-substances_en, accessed May 2018.
  6. Government of Canada, “Cosmetic Ingredient Hotlist: Prohibited and Restricted Ingredients,” https://www.canada.ca/en/health-canada/services/consumer-product-safety/cosmetics/cosmetic-ingredient-hotlist-prohibited-restricted-ingredients.html, accessed May 2018.
  7. California Department of Public Health, “California Safe Cosmetics Program Product Database,” https://safecosmetics.cdph.ca.gov/search/, accessed May 2018.
  8. California Department of Toxic Substances Control, “Safer Consumer Products,” http://www.dtsc.ca.gov/SCP/WhatIsTheSCPProgram.cfm, accessed May 2018.
  9. S. Department of Health and Human Services, National Toxicology Program, “Report on Carcinogens: Fourteenth Edition,” 2016. https://ntp.niehs.nih.gov/pubhealth/roc/index-1.html
  10. Masui, T., Hirose, M., Imaida, K., et al. (1986). Sequential changes of the forestomach of F344 rats, Syrian golden hamsters, and B6C3F1 mice treated with butylated hydroxyanisole. Jpn J Cancer Res 77(11): 1083-1090.
  11. Park, E.H., Chang, H.H., Cha, Y.N. (1990). Induction of hepatic tumors with butylated hydroxyanisole in the self-fertilizing hermaphroditic fish Rivulus ocellatus marmoratus. Jpn J Cancer Res 81(8): 738-741.
  12. S. Department of Labor, Occupational Safety and Health Administration, “Hair Smoothing Products That Could Release Formaldehyde,” 2011. https://www.osha.gov/SLTC/formaldehyde/hazard_alert.html
  13. Environmental Protection Agency, Agency for Toxic Substances and Disease Registry, “Toxicological Profile for 1,4-dioxane,” https://www.atsdr.cdc.gov/toxprofiles/tp187-c2.pdf
  14. Kasai, T., Kano, H., Umeda, Y., et al. (2009). Two-year inhalation study of carcinogenicity and chronic toxicity of 1,4-dioxane in male. Inhal Toxicol 21:889-897. doi:10.1080/08958370802629610
  15. Boberg, J., Taxvig, C., Christiansen, S., Hass, U. (2010), Possible endocrine disrupting effects of parabens and their metabolites. Reprod Toxicol. 2010 Sep;30(2):301-12. Epub 2010 Apr 8.
  16. Harvell, J., M. Bason and H. Maibach (1994). Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. (Table 2: Substances identified as capable of causing contact urticaria).
  17. Khanna S., Dash P. R. and Darbre P. D. (2014), Exposure to parabens at the concentration of maximal proliferative response increases migratory and invasive activity of human breast cancer cells in vitro, J. Appl. Toxicol., 34, pages 1051–1059. doi: 10.1002/jat.3003
  18. Jurewicz, J., PhD, Radwan, M., PhD, Wielgomas, B., PhD, et al. (2017). Human Semen Quality, Sperm DNA Damage, and the Level of Reproductive Hormones in Relation to Urinary Concentrations of Parabens [Abstract]. Journal of Occupational and Environmental Medicine, 59(11), 1034-1040. doi:10.1970
  19. Swan, S.H., Main, K.M., Liu, F., et al. (2005). Decrease in Anogenital Distance among Male Infants with Prenatal Phthalate Exposure. Environmental Health Perspectives. 2005;113(8):1056-1061. doi:10.1289/ehp.8100.
  20. Engel, S.M., Miodovnik, A., Canfield, R.L., et al. (2010). Prenatal Phthalate Exposure Is Associated with Childhood Behavior and Executive Functioning. Environmental Health Perspectives. 2010;118(4):565-571. doi:10.1289/ehp.0901470.
  21. Hauser, R., Meeker, J.D., Singh, N.P., Silva, M.J., Ryan, L., Duty, S., Calafat, A.M. (2007). DNA damage in human sperm is related to urinary levels of phthalate monoester and oxidative metabolites, Human Reproduction, 2007 22(3), 688–695, doi:10.1093
  22. Lin, B., Ou, M., Chung, S., Pang, C., & Chen, H. (2009). Adolescent toluene exposure produces enduring social and cognitive deficits in mice: An animal model of solvent-induced psychosis. The World Journal of Biological Psychiatry, 11(6), 792-802. doi:10.3109/15622970903406234
  23. Environmental Protection Agency, Agency for Toxic Substances and Disease Registry, “Medical Management Guidelines for Toluene,” https://www.atsdr.cdc.gov/mmg/mmg.asp?id=157&tid=29
  24. Clayton, E. M., Todd, M., Dowd, J. B., & Aiello, A. E. (2010). The Impact of Bisphenol A and Triclosan on Immune Parameters in the U.S. Population, NHANES 2003–2006. Environmental Health Perspectives, 119(3), 390-396. doi:10.1289/ehp.1002883
  25. Ruderman, J. (2010). Faculty of 1000 evaluation for Triclosan exposure modulates estrogen-dependent responses in the female wistar rat. F1000 – Post-publication Peer Review of the Biomedical Literature. doi:10.3410/f.4315956.4133054
  26. Shim, Y., Choi, J., Ahn, H., & Kwon, J. (2012). Effect of sodium lauryl sulfate on recurrent aphthous stomatitis: A randomized controlled clinical trial. Oral Diseases, 18(7), 655-660. doi:10.1111/j.1601-0825.2012.01920.x
  27. Black, R.E., Hurley, F.J, & Havery, D.C (2001). Occurrence of 1,4-Dioxane in Cosmetic Raw Materials and Finished Cosmetic Products. Journal Of AOAC International 84(3). PMID: 11417628
  28. CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.